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Irritable Bowel Syndrome (IBS)

Irritable bowel syndrome is a common cause of lower abdominal pain.  The frequency of comorbidity in fibromyalgia is 59% compared to 15 to 20% in the general population. About 70% of those affected by this disorder are women.1  It can be placed into one of three subgroups:  Constipation-predominant IBS; diarrhea-predominant IBS; and alternating bowel habits or “pain predominant” IBS.  This syndrome is a multisymptom complex that is manifested by alteration in bowel habit frequency, stool consistency, and associated abdominal discomfort (pain, cramping, bloating, etc.)  IBS treatments are usually based on trying to alleviate the predominant symptoms.  For instance, if the most common symptom is diarrhea, medication should help alleviate frequency, loose stools, etc.  If the main problem is constipation, then medication should help soften the bowel movement and increase frequency of bowel habits. Medications of choice fall into the following categories:  Antispasmodics, bulking agents, antidiarrheals, laxatives, tricyclic antidepressants, serotonin reuptake medications, 5-HT, antagonists and 5-HT, agonists.  The treating physician will choose the medication most closely associated with alleviating the patient’s IBS symptoms which should also help with the overall treatment of fibromyalgia symptoms.  As with any comorbid condition in fibromyalgia, it is imperative that symptoms which can be addressed and remedied are identified.  Alleviating these symptoms can help with the overall  quality of life experienced by fibromyalgia patients.

1Lacy, Sean R (2005). Weiner’s Pain Management, A Practical Guide for Clinicians, 7th edition, 371-379.


Dr. Andrew Holman:

Pramipexole A New Treatment for Fibr-
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